Functional/Serologic Test

3002

ABO and Rh

Testing for pretransfusion donor and patient compatibility and to assist in the diagnosis

2200

ABO and Rh - Transplant

Testing for donor and patient compatibility in the context of a organ or bone marrow transplant

2113

ABO Antibody Titer

ABO antibody titration tests for the assessment of prognosis in ABO-incompatible hematopoietic stem cell transplantation or for decision-making in ABO-incompatible kidney transplantation.

3024

ABO Antibody Titer

ABO antibody titration tests for the assessment of prognosis in ABO-incompatible hematopoietic stem cell transplantation or for decision-making in ABO-incompatible kidney transplantation.

1298

ADAMTS13 Activity

This assay is measured by Fluorescence Resonance Energy Transfer (FRET) with a synthetic substrate.

1299

ADAMTS13 Antibody

The antibody assay detects IgG antibody serologically by ELISA.

1295

ADAMTS13 Evaluation

ADAMTS13 Evaluation is a reflexive testing algorithm for evaluation of TTP. Activity is always performed. If result is <= 30%, the inhibitor assay (1297) is performed. If inhibitor result is <= 0.7 Inhibitor Units, the antibody assay (1299) is performed

1297

ADAMTS13 Inhibitor

The inhibitor assay measures antibodies that inhibit ADAMTS13 function by mixing study.

1500

aHUS Complement Profile

Includes: CD46 (MCP) Expression, C3, C4, Factor B, Factor H, Factor H Autoantibody, and Factor I

3060

Antibody Identification Problem

ABO/Rh, Direct Antiglobulin Test and one Ab ID. Based results determined by IRL, additional tests may include selected cell panel(s), selected cell screens(s), rare cell panel(s), and pertinent antigen typing(s).

3080

Antibody Titration Workup

Detects the presence and measures the amount of antibodies within a person’s blood. Monitoring antibody levels during pregnancy to help assess the risk of hemolytic disease of the newborn (HDN).

1191

Anticardiolipin Antibody

This assay is designed to detect anticardiolipin IgG and IgM isotypes.

1190

Antiphospholipid Antibody Profile

Includes: Lupus Anticoagulant, Anticardiolipin Antibody IgG and IgM and Beta 2 Glycoprotein I Antibody IgG and IgM.

1009

Arixtra® (Fondaparinux) Level

This test is only valid for monitoring patients on Arixtra (fondaparinux), not unfractionated heparin or low molecular weight heparin.

3997

Autoimmune Hemolytic Anemia

Testing to determine when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in the circulation.

1291

Beta 2 Glycoprotein I Antibody

This solid phase immunoassay is designed for detection of antibodies to ß2 Glycoprotein I.

1501

C3

Complement protein 3 (C3) is the central component of the complement system. Complement activation is associated with consumption of C3. Reduced serum concentrations of C3 may be seen in some patients with aHUS.

1502

C4

C4 levels may be useful in distinguishing systemic activation of the classical versus alternative complement pathways.

1507

CD46 (MCP) Expression

Measured using flow cytometry, very low CD46 expression is detected in patients with homozygous CD46 deficiency.

3018

Complete Rh Phenotyping of RBCs

Includes: D, C, c, E, e antigens.

2600

Crossmatch (Flow Cytometry)

The flow cytometric lymphocyte crossmatch is a technique for evaluating the compatibility of potential transplant recipients and donors and analyzed for the presence of bound IgG antibodies.

2610

Crossmatch (Flow Cytometry) Against Recipient

Recipient serum is incubated with donor lymphocytes which are analyzed in a flow cytometer for the presence of bound IgG antibodies to find donor-specific antibodies to avoid deleterious graft function.

2601

Crossmatch (Flow Cytometry) Titration

Titration allows you to determine the amount of antibody that gives you the best separation of populations in your samples, and the best measure of expression levels.

3111

DAT Negative Hemolytic Anemia Evaluation

Includes: ABO/Rh, Direct Antiglobulin Tests (including IgA detection), Elution (routine and enhanced), and antibody detection tests (routine and enhanced). Additional tests as necessary based upon results determined by Immunohematology Reference Lab.

3009

Direct Antiglobulin Test (DAT)

Also known as the direct Coombs test, is used primarily to help determine whether the cause of hemolytic anemia.

3011

Donath-Landsteiner

Detects harmful antibodies related to a rare disorder called paroxysmal cold hemoglobinuria. Not available as an individual test. Requires initial evaluation at additional cost.

9500

Drug-Dependent Neutrophil Antibody

This test determines if there is a drug dependent antibody that is binding to a patients neutrophils causing a neutropenia.

9000

Drug-Dependent Platelet Antibody

This assay employs flow cytometric detection of drug-dependent platelet antibodies for several drugs.

3110

Drug-Dependent RBC Antibody Study

Evaluation of immune hemolysis after exposure to certain drugs is important in order to make the correct diagnosis and to prevent possible future adverse complications.Not available as an individual test. Requires initial evaluation at additional cost.

3020

Elution

Used for dissociating an antibody that is attached to the surface of a red blood cell. Used in identification of complicated antibodies, the workup of transfusion reactions or hemolytic disease of the newborn, and the workup of warm autoantibodies.

1503

Factor B

Reduced Factor B levels are indicative of alternate pathway activation in complement-mediated diseases, including aHUS.

1505

Factor H

Decreased Factor H plasma levels (and/or mutations in Factor H) have been associated with a number of complement-mediated diseases, including aHUS.

1506

Factor H Autoantibody

Patients may develop autoantibodies to Factor H that may clear Factor H from circulation, or otherwise reduce control of the complement system, accounting for approximately 6% of all aHUS cases.

1504

Factor I

This control protein regulates complement production. Low levels (less than 60% of normal are indicative of a quantitative deficiency in complement-mediated diseases, including aHUS.

1021

Factor II Activity

This assay measures activity of factor II.

1025

Factor II Inhibitor Profile

This order includes both Factor II Activity and Factor II Inhibitor.

1091

Factor IX Activity

This assay measures activity of factor IX.

1093

Factor IX Activity - Hepzyme Treated

This assay measures activity of factor IX, with addition of hepzyme to neutralize the influence of heparin.

1095

Factor IX Inhibitor Profile

This order set includes both Factor IX Activity and Factor IX Inhibitor.

1094

Factor IX Inhibitor Profile - Hepzyme Treated

This order set includes both Factor IX Activity and Factor IX Inhibitor, both including the addition of hepzyme to neutralize the influence of heparin.

1051

Factor V Activity

This assay measures activity of factor V.

1055

Factor V Inhibitor Profile

This order set includes both Factor V Activity and Factor V Inhibitor.

1035

Factor V Leiden (G1691A)

This molecular test evaluates individuals for the germline Factor V Leiden variant (F5 c. 1601G7A, p.Arg534Gln; Legacy nomenclature G1691A), which is associated with an increased risk of venous thromboembolism.

1071

Factor VII Activity

This assay measures activity of factor VII.

1075

Factor VII Inhibitor Profile

This profile includes: Factor VII Activity and Factor VII Inhibitor.

1135

Factor VIII Activity - Chromogenic

The chromogenic factor VIII activity assay uses bovine reagents, is insensitive to emicizumab and lupus anticoagulant, and is adversely affected by the presence of direct factor X inhibitors or high concentrations of heparin.

1081

Factor VIII Activity - Clot based

This test measures the activity of factor VIII to aid in diagnosis of hemophilia A, acquired factor VIII deficiency, or as part of diagnostic workup for von Willebrand disease (VWD).

1315

Factor VIII Activity - Concentrate

This test is used to determine the level of the coagulation protein Factor VIII in a vial of factor concentrate.

1310

Factor VIII Activity - Cryoprecipitate

This test is used to determine the level of the coagulation protein Factor VIII in a unit or pool of cryoprecipitate. Contact laboratory for additional information.

1342

Factor VIII Activity - Plasma QC

This test is used to determine the level of the coagulation protein Factor VIII in a unit or Fresh Frozen Plasma or Recovered Plasma. Contact laboratory for additional information.

1136

Factor VIII Activity Hepzyme Treated - Chromogenic

The chromogenic factor VIII activity assay uses bovine reagents, is insensitive to emicizumab and lupus anticoagulant, and is adversely affected by the presence of direct factor X inhibitors or very high concentrations of heparin (greater than 2 U/mL). The addition of hepzyme in this assay will neutralize the influence of heparin.

1082

Factor VIII Activity Hepzyme Treated - Clot based

This assay measures activity of factor VIII, with addition of hepzyme to neutralize the influence of heparin.

1137

Factor VIII Inhibitor

The chromogenic factor VIII inhibitor assay uses bovine reagents, is insensitive to emicizumab and lupus anticoagulant, and is adversely affected by the presence of direct factor X inhibitors or high concentrations of heparin.

1138

Factor VIII Inhibitor - Hepzyme Treated

The chromogenic factor VIII inhibitor assay uses bovine reagents, is insensitive to emicizumab and lupus anticoagulant, and is adversely affected by the presence of direct factor X inhibitors or very high concentrations of heparin (greater than 2 U/mL). The addition of hepzyme in this assay will neutralize the influence of heparin.

1101

Factor X Activity

This assay measures activity of factor X.

1105

Factor X Inhibitor Profile

This order set includes: Factor X Activity and Factor X Inhibitor.

1111

Factor XI Activity

This assay measures activity of factor XI.

1115

Factor XI Inhibitor Profile

This order set includes: Factor XI Activity and Factor XI Inhibitor.

1121

Factor XII Activity

This assay measures activity of factor XII.

1125

Factor XII Inhibitor Profile

This order set includes: Factor XII Activity and Factor XII Inhibitor.

1011

Fibrinogen Activity

This assay measures fibrinogen activity. If both Fibrinogen Activity and Fibrinogen Antigen are ordered on the same specimen, a ratio result is also reported.

1320

Fibrinogen Activity - Cryoprecipitate

This test is used to determine the level of the coagulation protein Fibrinogen in a unit or pool of cryoprecipitate. Contact laboratory for additional information.

1012

Fibrinogen Antigen

If both Fibrinogen Activity and Fibrinogen Antigen are ordered on the same specimen, a ratio result is also reported.

5444

Glycoprotein IV (CD36) Typing

This assay utilizes flow cytometry in the typing of platelet glycoprotein IV (CCD36).

3100

Hemolytic Disease of the Newborn (HDN)

Serological analysis post-delivery to determine compatibility of mother and baby when Hemolytic Disease of the Newborn is suspected.

5514

Heparin-Dependent Platelet Antibody (PF4 ELISA) - IgA/M Panel

This Platelet Factor Four Enzyme Linked Immunosorbent Assay is designed for detection of Heparin-Dependent Platelet Antibodies of the IgM or IgA subclasses.

5510

Heparin-Dependent Platelet Antibody (PF4 ELISA) - IgG

This Platelet Factor Four Enzyme Linked Immunosorbent Assay is designed for detection of Heparin-Dependent Platelet Antibodies of the IgG subclass.

5502

Heparin-Induced Thrombocytopenia - PEA

This test is designed to detect heparin-dependent platelet antibodies in the serum from patients suspected of having Heparin-Induced Thrombocytopenia (HIT).

5508

Heparin-Induced Thrombocytopenia - SRA

This test is designed to detect heparin-dependent platelet antibodies in the serum from patients suspected of having Heparin-Induced Thrombocytopenia (HIT).

5509

Heparin-Induced Thrombocytopenia Evaluation (SRA)

Heparin-Induced Thrombocytopenia Evaluation is a reflexive algorithm. IgG-PF4 ELISA is always performed. If ELISA results are non-negative a Serotonin Release Assay will be performed.

2235

HLA Antibody Detection (Flow Cytometry)

HLA antigen testing for solid organ and stem cell transplants.

5002

HOLD TRALI Recipient

Versiti Wisconsin, Inc will HOLD a recipient whole blood sample during TRALI donor testing. If an antibody is identified in the donor, the recipient sample could be genotyped to confirm presence of the target antigen by client's request.

1192

Lupus Anticoagulant

Includes: Silica Clotting Time (SCT) and dilute Russell's Viper Venom Time (dRVVT) screen and confirmatory studies; mixing studies if indicated.

5126

Neonatal Alloimmune Neutropenia (NAN) Panel - Father

This panel includes: Neutrophil Antigen Genotyping - HNA-1, 3, 4 and 5.

5125

Neonatal Alloimmune Neutropenia (NAN) Panel - Mother

This panel includes: Neutrophil Antigen Genotyping - HNA-1, 3, 4 and 5, and Neutrophil Antibody Identification and HLA Antibody Screen.

5703

Neonatal Alloimmune Thrombocytopenia (NAIT)-Initial Paternal

This order set includes: Platelet Antigen Genotyping Panel. To complete this workup, order Neonatal Alloimmune Thrombocytopenia (NAIT)-Initial Testing Maternal with Paternal (test code 5603) for maternal sample.

5303

Neonatal Alloimmune Thrombocytopenia (NAIT)-Initial Testing Maternal Only

This order set includes: Platelet Antigen Genotyping Panel and Platelet Antibody Identification Panel. Order this test when the father is not available for testing.

5603

Neonatal Alloimmune Thrombocytopenia (NAIT)-Initial Testing Maternal with Paternal

This order set includes: Platelet Antigen Genotyping on parents, Platelet Antibody Identification Panel on mother and maternal serum crossmatched with paternal platelets. To complete the workup, concurrently order NAIT-Initial Paternal (test code 5703)

5630

Neonatal Alloimmune Thrombocytopenia (NAIT)-Serial Monitoring Maternal only

This assay includes: Testing for antibodies against HPA-1a/b, HPA-2a/b, HPA-3a/b, HPA-4a, HPA-5a/b, GPIIb/IIIa, GPIa/IIa, GPIb/IX. GPIV and Class I HLA.

5640

Neonatal Alloimmune Thrombocytopenia (NAIT)-Serial Monitoring Maternal with Paternal

This order set includes: Platelet Antibody Identification Panel on mother and maternal serum crossmatched with paternal platelets.

5113

Neutrophil Antibody Identification and HLA Antibody Screen

This order set includes: Neutrophil Antibody Identification and HLA Antibody Detection.

5102

Neutrophil Antibody Screen

This flow-cytometry screen tests for the detection and identification of neutrophil antibodies.

5112

Neutrophil Antibody Screen and HLA Antibody Screen

This order set includes: Neutrophil Antibody Screen and HLA Antibody Detection. Automatic reflexing options are available.

5119

Neutrophil Antibody Screen with REFLEX to 5113 (Neut ID and HLA Screen)

This order will automatically reflex to Neutrophil Antibody Identification and HLA Detection if neutrophil reactive antibodies are detected.

5110

Neutrophil Antibody Screen with REFLEX to HLA Antibody Screen

This order will automatically reflex to HLA Detection if neutrophil reactive antibodies are detected.

3240

Partial RhD Analysis

Mutations in RHD may result in amino acid substitutions in the D protein. If those substances change the appearance or structure of exposed parts of the antigen on the outside of the RBC (epitopes), the patient is described as having partial D.

1175

Platelet Aggregation

Used to assess platelet function if a hereditary bleeding disorder is suspected. Includes: Aggregation with Ristocetin; Aggregation and ATP Release w/ ADP, Collagen, Thrombin and Arachidonic Acid. Platelets must be tested within four (4) hours of draw

5608

Platelet Antibody Identification Panel

This panel includes: Testing for antibodies against HPA-1a/b, HPA-2a/b, HPA-3a/b, HPA-4a, HPA-5a/b, GPIIb/IIIa, GPIa/IIa, GPIb/IX, GPIV and Class I HLA.

5543

Platelet Antibody Screen

This assay screens patient sera for platelet-reactive antibodies via flow cytometry.

5544

Platelet Autoantibodies

This assay detects direct and indirect glycoprotein-specific antibodies in eluates prepared from washed patient platelets.

5545

Platelet Glycoprotein Expression (PGE)

This order includes: GPIb (Bernard Soulier Syndrome) and GPIIb/IIIa (Glanzmann Thrombasthenia).

5632

Platelet Transfusion Refractory (PTR) Panel

This panel includes: Platelet Antibody Identification Panel and Platelet Antigen Genotyping Panel.

5550

PNH - Erythrocytes and Leukocytes

Flow cytometric evaluation of both erythrocytes and leukocytes in evaluation for paroxysmal nocturnal hemoglobinuria (PNH)

5549

PNH - Leukocytes

Flow cytometric evaluation of leukocytes in evaluation for paroxysmal nocturnal hemoglobinuria (PNH)

1086

Porcine Factor VIII Inhibitor Profile

This order set includes both Factor VIII Activity-Clot based and Porcine Factor VIII Inhibitor.

1084

Porcine Factor VIII Inhibitor Profile - Hepzyme Treated

This order set includes both Factor VIII Activity-Clot based and Porcine Factor VIII Inhibitor, with addition of hepzyme to neautralize the influence of heparin

5631

Post-Transfusion Purpura (PTP) Panel

Includes: Platelet Antibody Identification Panel and Platelet Antigen Genotyping Panel.

1031

Protein C Activity

This test provides the activity level of the blood coagulation factor, Protein C. This protein is one of the regulatory proteins in the blood clotting cascade.

1033

Protein C Antigen

This test provides the antigen level of the blood coagulation factor, Protein C. This protein is one of the regulatory proteins in the blood clotting cascade.

1041

Protein S Activity

This test provides the activity level of the blood coagulation factor, Protein S. This protein is one of the regulatory proteins in the blood clotting cascade.

1043

Protein S Antigen, Free

This test provides the antigen level of the blood coagulation factor, Protein S. This protein is one of the regulatory proteins in the blood clotting cascade.

1042

Protein S Antigen, Total and Free

This test provides the antigen level of the blood coagulation factor, Protein S. This protein is one of the regulatory proteins in the blood clotting cascade.

1068

Ristocetin-Induced Platelet Aggregation (RIPA)

Aggregation with high and low dose ristocetin is used to identify patients with type 2B von Willebrand Disease, platelet-type von Willebrand Disease or Bernard-Soulier Syndrome. Citrated whole blood (light-blue top)

1260

Single Platelet Agonist Aggregation - ADP

Used to assess platelet function if a hereditary bleeding disorder is suspected. This test is used to determine how a patients platelets respond to the agonist ADP. Patients platelets must be tested within four (4) hours of draw.

1255

Single Platelet Agonist Aggregation - Arachidonic Acid

Used to assess platelet function if a hereditary bleeding disorder is suspected. This test is used to determine how a patients platelets respond to the agonist ADP. Patients platelets must be tested within four (4) hours of draw.

1270

Single Platelet Agonist Aggregation - Collagen

Used to assess platelet function if a hereditary bleeding disorder is suspected. This test is used to determine how a patients platelets respond to the agonist ADP. Patients platelets must be tested within four (4) hours of draw.

1250

Single Platelet Agonist Aggregation - Thrombin

Used to assess platelet function if a hereditary bleeding disorder is suspected. This test is used to determine how a patients platelets respond to the agonist Thrombin. Patients platelets must be tested within four (4) hours of draw.

3021

Thermal Amplitude Study

Not available as an individual test. Requires initial evaluation at additional cost.

1007

Thrombosis Profile

This panel order set includes Anticardiolipin Antibody, Factor V Leiden, Lupus Anticoagulant, Protein C Activity, Protein S Activity, Prothrombin Gene Mutation and Beta 2 Glycoprotein I Antibody.

5506

Vaccine-Induced Immune Thrombotic Thrombocytopenia - SRA Panel

This SRA Panel includes testing with and without heparin.

5515

VITT Workup (PF4 IgG - Reflex to VITT SRA Panel)

VITT Workup is a reflexive algorithm. IgG-PF4 ELISA is always performed. If ELISA results are non-negative Serotonin Release Assays with and without heparin will be performed.

1060

von Willebrand Profile

This profile order set includes: Factor VIII Activity, VWF Antigen, VWF GPIbM Activity and VWF Quantitative Multimer.

1800

VWD Diagnostic Evaluation

Reflexive algorithm always includes: FVIII Activity, VWF Antigen, VWF GPIbM Activity, and VWF Collagen III Binding. Reflex testing may include: VWD Type 2B Binding, VWD Type 2N Binding, VWF Propeptide Antigen, and/or VWF Quantitative Multimer

1067

VWD Type 2B Evaluation

This order set includes VWD Type 2B Binding and VWD Type 2B Quantitative Multimer.

1089

VWD Type 2N Binding

This 2N-von Willebrand Disease panel is designed to distinguish type 2N-von Willebrand disease from mild hemophilia A and hemophilia A carriers.

1088

VWD Type 2N Profile

This order set includes: Factor VIII Activity, VWF Antigen and VWD Type 2N Binding.

1062

VWF Antigen

This assay measures a patient's total vWF protein level, independent of the multimer composition of the plasma

1279

VWF Collagen Binding Profile

This assay tests the capacity of platelet adhesion at sites of blood vessel injury and can identify qualitative binding issues. Includes VWF Antigen, VWF Collagen III Binding, and VWF Collagen IV Binding. Additional reflex to VWF Quantitative Multimer, if indicated.

1281

VWF Collagen III Binding

This assay tests the capacity of platelet adhesion at sites of blood vessel injury and can identify qualitative binding issues.

1280

VWF Collagen IV Binding

This assay tests the capacity of platelet adhesion at sites of blood vessel injury and can identify qualitative binding issues.

1070

VWF GPIbM Activity

This ristocetin-independent activity assay is an alternative to VWF Ristocetin Cofactor Activity with superior precision and sensitivity.

1065

VWF Inhibitor Profile

This order set includes VWF Inhibitor Screen mixing study and VWF GPIbM Activity. If the VWF GPIbM result is >= 50 IU/dL, the inhibitor screen is invalid and will be cancelled and credited.

1282

VWF Propeptide Antigen

This assay evaluates propeptide antigen levels. This result should be correlated with VWF antigen, VWF ristocetin cofactor activity, VWF multimers, and clinical history by the ordering physician to arrive at the appropriate diagnosis.

1063

VWF Quantitative Multimer

Quantitative multimer analysis provides an objective measure of VWF structure to characterize subtle changes observed in the subtypes of VWD and may help to determine the nature of any additional clinical laboratory testing to reach a clear-cut diagnosis

3040

Weak RhD Analysis Workup

This complex test is ordered to resolve a Rh discrepancy (aka D antigen typing discrepancy). The molecular testing will identify Weak D Types 1, 2, and 3. These Weak D Types can be safely deemed Rh positive.