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The chromogenic factor VIII inhibitor assay uses bovine reagents, is insensitive to emicizumab and lupus anticoagulant, and is adversely affected by the presence of direct factor X inhibitors or high concentrations of heparin. USA test status: This is a laboratory developed test (LDT). 

Functional/Serologic Test

Citrated Plasma (light blue top)

1.5 mL

1 mL

Chromogenic Bethesda Titer

7 days

Yes

No