Chimerism Testing For Engraftment
Rapid and highly sensitive chimerism lab tests for post-transplant monitoring.
Chimerism occurs when a person’s body contains two different sets of DNA. Versiti Diagnostic Labs offers sophisticated chimerism testing for post-transplant patients, including those who received solid organ transplantation, bone marrow transplantation and cellular therapy treatments.
Versiti Diagnostic Laboratories’ expertise includes:
We support our transplant partners by helping to monitor the relative amounts of recipient and donor cells after transplantation. Important clinical events in allogenic bone marrow transplantation, such as engraftment, relapse and the effects of post-transplant therapies, can be monitored on a molecular level by using inherent genetic differences between recipients and donors.
Versiti Diagnostic Labs’ genetic chimerism testing has proven reliability, demonstrated by consistent, accurate, precise performance in proficiency programs.
Enriched cell populations can also be used to monitor patients following hematopoietic stem cell transplant for more precise detection of changes in transplant dynamics. Testing for the following cell subtypes is available:
| Cell Marker | Cell Subset |
| CD3 | T cells |
| CD19 | B cells |
| CD33 (incl. CD66b) | Myeloid cells |
| CD56 | Natural Killer cells |