1200

aHUS/DDD Genetic Evaluation

Coding regions and splice sites of the following genes are sequenced: CFH, CFI, MCP(CD46), THBD, C4BPA, C4BPB, CFB, C3, DGKE, ADAMTS13, CFHR1, CFHR3, CFHR4 and CFHR5.

4865

Autosomal Dominant Thrombocytopenia Panel

This panel is designed for detection of germline variants in 22 genes known to cause thrombocytopenia, specifically inherited in an autosomal dominant manner. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4880

Bernard-Soulier Syndrome Panel

This panel is designed for the detection of germline variants in 3 genes known to cause Bernard-Soulier syndrome. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

3850

C/c Genotyping

Genotyping for the Rh C and c antigen, used in the context of hemolytic disease of the newborn or fetus

2046

CD19 & CD56 Engraftment Analysis by Chimerism Testing

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

2042

CD19 Engraftment Analysis by Chimerism Testing

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

2044

CD3 & CD33 Engraftment Analysis by Chimerism Testing

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

2040

CD3 Engraftment Analysis by Chimerism Testing

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

2045

CD3, CD33, & CD56 Engraftment Analysis by Chimerism Testing

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

2041

CD33 Engraftment Analysis by Chimerism Testing

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

2043

CD56 Engraftment Analysis by Chimerism Testing

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

4815

Coagulation Disorder Panel

This panel is designed for the detection of germline variants in 19 genes and one targeted variant known to cause coagulation disorders. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4825

Comprehensive Bleeding Disorder Panel

This panel is designed for the detection of germline variants in 66 genes and one targeted variant by aCGH known to cause bleeding due to disorders of coagulation, platelet function, and/or hereditary hemorrhagic telangiectasia (HHT). It can be ordered as: Next Generation Sequencing (NGS) only*; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only. (* Includes PLAU performed by aCGH)

4830

Comprehensive Platelet Disorder Panel

This panel is designed for the detection of germline variants in 63 genes known to cause platelet function disorders and/or inherited thrombocytopenia. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4845

Congenital Neutropenia Panel

This panel is designed for detection of germline variants in 35 genes known to cause severe congenital neutropenia (SCN), including cyclic neutropenia, non-syndromic neutropenia and syndromic neutropenia with non-hematological manifestations. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4850

Custom Blood Disorder Panel

Sequence analysis of genes included in any Hematology Genetics panel can be ordered as a custom panel (2-10 genes), as dictated by the patient's clinical and laboratory phenotype. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

3870

Doa/Dob Genotyping

Genotyping for the Dombrock antigens, used in the context of hemolytic disease of the newborn or fetus

3852

E/e Genotyping

Genotyping for the Rh E and e antigens, used in the context of hemolytic disease of the newborn or fetus

4220

Engraftment Post-Transplant Evaluation - Blood

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

4222

Engraftment Post-Transplant Evaluation - Bone Marrow

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

4232

Engraftment Post-Transplant Evaluation - Other

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

4040

Engraftment Pre-Transplant Analysis: Donor

4020

Engraftment/Chimerism Testing: Pre-Transplant Evaluation

Engraftment pre-transplant testing for informative locus is required for post-transplant to be possible. Pre-transplant testing is performed on donor and recipient samples. Pre-transplant order code (4020) should not be placed on same encounter as post-transplant order codes.

4250

Erythroid Chimerism

Monitor erythroid lineage chimerism in patients with sickle cell disease (SCD) following allogeneic bone marrow transplantation. Hemoglobin genotyping of donor and recipient can be done by Test#4624 Hemoglobin SC Mutation Analysis. Indicate on requisition Donor and Patient genotype.

1035

Factor V Leiden (G1691A)

This molecular test evaluates individuals for the germline Factor V Leiden variant (F5 c. 1601G7A, p.Arg534Gln; Legacy nomenclature G1691A), which is associated with an increased risk of venous thromboembolism.

1401

Factor VIII (F8) Intron 1 Inversion Analysis

F8 intron 1 Inversion Analysis is appropriate for individuals with a family history of severe hemophilia A known to be caused by this pathogenic variant.

1400

Factor VIII (F8) Intron 22 Inversion Analysis

F8 intron 22 Inversion Analysis is appropriate for individuals with a family history of severe hemophilia A known to be caused by this pathogenic variant.

1402

Factor VIII (F8) Inversion Analysis

Factor 8 (F8) inversion analysis evaluates both the intron 1 and intron 22 inversions, and is recommended only for males with severe hemophilia A, or females who have a family history of severe unknown type of hemophilia A, or females with low factor VIII levels who have no known family history of hemophilia. This assay is included in the Factor VIII (F8) severe HA Analysis-Reflex test. F8 variants other than inversions are not detected by this assay.

1403

Factor VIII (F8) Severe HA Analysis-Reflex

This testing is recommended for the detection of germline variants associated with severe Hemophilia A . Testing begins with F8 inversion Analysis; if this analysis is negative, F8 Sequence Analysis is performed at an additional charge. Refer to F8 Inversion Analysis and F8 Sequence Analysis for test information.

4885

Fibrinogen Disorders Panel

This panel is designed for the detection of germline variants in 3 genes known to cause inherited qualitative or quantitative disorders of fibrinogen. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4860

Fibrinolytic Disorder Panel

This panel is designed for the detection of germline variants in 8 genes and one targeted variant known to cause delayed bleeding due to hyperfibrinolysis. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

3860

Fya/Fyb Genotyping

Genotyping for the Duffy (Fya, Fyb) antigens, used in the context of hemolytic disease of the newborn or fetus

4870

Glanzmann Thrombasthenia Panel

This panel is designed for the detection of germline variants in 2 genes known to cause Glanzmann thrombasthenia. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4624

Hemoglobin SC Mutation Analysis

Sickle Cell Disease is caused by mutations in the b-globin gene (HBB) and are defined by the presence of hemoglobin S (HbS). Molecular prenatal testing can be offered for pregnancies at increased risk.

4895

Hereditary Hemorrhagic Telangiectasia Panel

This panel is designed for the detection of germline variants in 6 genes known to cause hereditary hemorrhagic telangiectasia:  Next Generation Sequencing (NGS) only;  NGS with reflex to Array Comparative Genomic Hybridization (aCGH);  NGS with concurrent aCGH (both testing methodologies performed simultaneously);  aCGH only

4875

Hermansky-Pudlak Syndrome Panel

This panel is designed for the detection of germline variants in 10 genes known to cause Hermansky-Pudlak syndrome. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

2380

HLA Haplotype by STR

A rapid screening test for potential sibling donors for blood & marrow transplant patients. The test must be ordered for the patient and each potential donor.

2300

HLA High Resolution Panel by NGS

High Resolution typing for HLA-A, HLA-B, HLA-C, HLA-DRB1, HLA-DRB3,4,5, HLA-DQA1, HLA-DQB1, HLA-DPA1, and HLA-DPB1 loci by next generation DNA sequencing (NGS).

2349

HLA Panel by NGS (Data Only)

2270

HLA Typing for Narcolepsy

HLA typing for presence of HLA loci associated with narcolepsy.

2324

HLA-A High Resolution

High Resolution typing for Class I HLA-A loci.

2504

HLA-A Intermediate Resolution

Intermediate Resolution typing for Class I HLA-A loci.

2304

HLA-A Low Resolution

Low Resolution typing for Class I HLA-A loci.

2279

HLA-A*02:01 Determination

Test for disorders or drug sensitivity associated with HLA-A*02:01 allele. HLA A-High Resolution Typing may be required for confirmation of the allele and an additional charge is incurred.

2520

HLA-A,B Intermediate Resolution

Intermediate Resolution typing for Class I HLA-A,B loci.

2303

HLA-A,B Low Resolution

Low Resolution typing for Class I HLA-A,B loci.

2329

HLA-A,B,C High Resolution

High Resolution typing for Class I HLA-A,B,C, loci.

2302

HLA-A,B,C Low Resolution

Low Resolution typing for Class I HLA-A,B,C, loci.

2274

HLA-A29 Determination

Test for disease associated with HLA-A29 allele which may be present in Birdshot chorioretinopathy (BSCR).

2325

HLA-B High Resolution

High Resolution typing for Class I HLA-B loci.

2505

HLA-B Intermediate Resolution

Intermediate Resolution typing for Class I HLA-B loci.

2305

HLA-B Low Resolution

Low Resolution typing for Class I HLA-B loci.

2276

HLA-B*15:02 Determination

Test for HLA-B*15:02 allele presence or absence for patients that may be prescribed Carbamazepine and Oxcarbazepine to avoid possible adverse reactions. HLA B-High Resolution Typing may be required for confirmation of the allele for an additional fee.

2272

HLA-B*57:01 Determination

The HLA-B*57:01 Determination test utilizes a low resolution method. If a possible HLA-B*57:01 allele is identified, HLA B-High Resolution Typing may be required for confirmation of the allele and an additional charge is incurred.

2319

HLA-B,DRB1 Verification Typing

Intermediate Resolution typing for HLA-B, DRB1.

2271

HLA-B27 Determination

Test for disorders associated with HLA-B27 allele such as Spondyloarthritis.

2275

HLA-B51 Determination

Test for disorders associated with HLA-B51 allele such as Behcet Disease (BD).

2326

HLA-C High Resolution

High Resolution typing for Class I HLA-C loci.

2506

HLA-C Intermediate Resolution

Intermediate Resolution typing for Class I HLA-C loci.

2306

HLA-C Low Resolution

Low Resolution typing for Class I HLA-C loci.

2323

HLA-DPB1 High Resolution

High Resolution typing for Class II HLA-DPB1 loci.

2513

HLA-DPB1/-DPA1 Intermediate Resolution

Intermediate Resolution typing for Class II HLA-DPB1 and DPA1 loci.

2318

HLA-DPB1/-DPA1 Low Resolution

Low Resolution typing for Class II HLA-DPB1/DPA1 loci.

2277

HLA Typing for Celiac Disease

Test for predisposition to Celiac Disease.

2328

HLA-DQB1 High Resolution

High Resolution typing for Class II HLA-DQB1 loci.

2308

HLA-DQB1,DQA 1 Low Resolution

Low Resolution typing for Class II HLA-DQB1, DQA1 loci.

2508

HLA-DQB1,DQA1 Intermediate Resolution

Intermediate Resolution typing for Class II HLA-DQB1, DQA1 loci.

2322

HLA-DRB1 High Resolution

High Resolution typing for Class II HLA-DRB1 loci.

2507

HLA-DRB1 Intermediate Resolution

Intermediate Resolution typing for Class II HLA-DRB1 loci.

2307

HLA-DRB1 Low Resolution

Low Resolution typing for Class II HLA-DRB1 loci.

2361

HLA-DRB1 Single Antigen - Disease Association

Identification for HLA disease associated with HLA-DRB1 allele.

2553

HLA-DRB1,DQB1,DQA1 Low Resolution

Low Resolution typing for Class II HLA-DRB1,DQB1,DQA1 loci.

5252

HLA-DRB3 (DR52) Determination

Identification for HLA disease associated with HLA-DRB3 allele.

2321

HLA-DRB3,4,5 Intermediate Resolution

Intermediate Resolution typing for Class II HLA-DRB3,4,5 loci.

2122

HLA-DRB3,4,5 Low Resolution

Low Resolution typing for Class II HLA-DRB3,4,5 loci.

2377

HLA-KIR Genotyping

DNA based typing to identify the presence of killer cell immunoglobulin-like receptors (KIR) genes.

4840

Inherited Thrombocytopenia Panel

This panel is designed for the detection of germline variants in 42 genes known to cause inherited thrombocytopenia. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

3862

Jka/Jkb Genotyping

Genotyping for the Kidd (Jka, Jkb) antigens, used in the context of hemolytic disease of the newborn or fetus

3858

Jsa/Jsb Genotyping

Genotyping for the Kell (Jsa, Jsb) antigens, used in the context of hemolytic disease of the newborn or fetus

3854

K/k Genotyping

Genotyping for the Kell (K, k) antigens, used in the context of hemolytic disease of the newborn or fetus

3856

Kpa/Kpb Genotyping

Genotyping for the Kell (Kpa, Kpb) antigens, used in the context of hemolytic disease of the newborn or fetus

3868

Lua/Lub Genotyping

Genotyping for the Lutheran (Lua, Lub) antigens, used in the context of hemolytic disease of the newborn or fetus

3864

M/N Genotyping

Genotyping for the M and N antigens, used in the context of hemolytic disease of the newborn or fetus

2048

MNC Separation and Engraftment Analysis

Contact laboratory if STAT testing is needed. Engraftment pre-transplant testing for informative locus is required for post-transplant and STAT testing to be possible.

5250

Neutrophil Antigen Genotyping - HNA-1

This DNA-based typing assay is for the HNA-1 Alloantigen system.

5203

Neutrophil Antigen Genotyping - HNA-3

This DNA-based typing assay is for the HNA-3 Alloantigen system.

5204

Neutrophil Antigen Genotyping - HNA-4

This DNA-based typing assay is for the HNA-4 Alloantigen system.

5205

Neutrophil Antigen Genotyping - HNA-5

This DNA-based typing assay is for the HNA-5 Alloantigen system.

5201

Neutrophil Antigen Genotyping Panel

This genotyping panel includes: Neutrophil Antigen Genotyping for HNA-1, 3, 4 and 5.

5519

Platelet Antigen Genotyping - HPA-1

Single alloantigen typing for HPA-1

5215

Platelet Antigen Genotyping - HPA-15

Single alloantigen typing for HPA-15

5523

Platelet Antigen Genotyping - HPA-2

Single alloantigen typing for HPA-2

5520

Platelet Antigen Genotyping - HPA-3

Single alloantigen typing for HPA-3

5521

Platelet Antigen Genotyping - HPA-4

Single alloantigen typing for HPA-4

5522

Platelet Antigen Genotyping - HPA-5

Single alloantigen typing for HPA-5

5524

Platelet Antigen Genotyping - HPA-6

Single alloantigen typing for HPA-6

5209

Platelet Antigen Genotyping - HPA-9

Single alloantigen typing for HPA-9

5600

Platelet Antigen Genotyping Panel

This genotyping panel includes 8 alloantigen systems: HPA-1, 2, 3, 4, 5, 6, 9 and 15.

4835

Platelet Function Disorder Panel

This panel is designed for the detection of germline variants in 41 genes known to cause inherited platelet dysfunction. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

1024

Prothrombin Gene Mutation (G20210A)

This molecular test evaluates individuals for the prothrombin G20210A variant (F2 c.*97G7>A) associated with increased risk of venous thromboembolism

3530

Red Cell Genotyping Panel

Red Cell Genotyping Panel: 72 PCR-hybridization probes are used in 36 polymerase chain reactions to identify the alleles associated with 44 blood group antigens.

3872

RhD Genotyping

Molecular characterization of the the RH genes as an aid to the clinical management of HDFN.

3874

RhD Zygosity

Determining RHD zygosity of a father is valuable for the management of HDN related to anti-D. Our robust clinical assay for RHD zygosity uses molecular techniques. The assay is suitable for use in both Caucasian and African-American patients.

3866

S/s Genotyping

Genotyping for the S and s antigens, used in the context of hemolytic disease of the newborn or fetus

4855

Single Gene Sequence Analysis

Single-gene sequencing is offered for most genes in Versiti's Hematology Genetics menu. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4970

Targeted Familial Variant Analysis

Targeted genetic analysis is used to determine if a specific familial variant is present. Testing is only available for genes tested by Next Generation sequencing at Versiti Wisconsin, Inc., a sample from an affected relative must be provided a copy of the family member's lab report for the variant being tested.

4820

Thrombosis Panel

This panel is designed for the detection of germline variants in 12 genes and 2 targeted variants known to be associated with an increased risk for developing venous thromboembolism. It can be ordered as: Next Generation Sequencing (NGS) only; NGS with reflex to Array Comparative Genomic Hybridization (aCGH); NGS with concurrent aCGH (both testing methodologies performed simultaneously); aCGH only

4060

Twin Zygosity Analysis

Monozygotic twins originate from a single fertilized ovum dividing into two embryos, while dizygotic twins result from ovulation of two eggs during a single menstrual cycle.

1289

VWD Platelet-Type Sequence Analysis

This test for platelet-type VWD provides sequencing of the full coding region (plus 30bp into the introns) of GPIBA.

1288

VWD Type 2N Sequence Analysis

Sequence analysis of VWF exons 17-21 and 24-27 detects germline variants associated with type 2N von willebrand disease (VWD).

1284

VWF Exon 28 Sequence Analysis (For Type 2M or 2B VWD)

Sequence Analysis of VWF exon 28 detects germline variants associated with type 2B or type 2M von Willebrand disease (VWD).