4624

Hemoglobin SC Mutation Analysis

Order Code: 4624 Get Requisition Form
Test Information Icon
Test Information
Sickle Cell Disease is caused by mutations in the b-globin gene (HBB) and are defined by the presence of hemoglobin S (HbS). Molecular prenatal testing can be offered for pregnancies at increased risk.
Also Known As Icon
Also Known As
  • HbS
  • HbSC
  • Hemoglobin S
  • Sickle Cell
Test Type Icon
Test Type
Genetic Test
Sample Notes Icon
Sample Notes
EDTA Whole Blood, EDTA Bone Marrow, DNA, Buccal Swabs, Amniotic Fluid, Cultured Amniocytes, Direct or Cultured CVS
Requested Volume Icon
Requested Volume
Fetal: 7-15 ml Amniotic Fluid or 5-10 mg CVS, backup culture of Amniocytes or CVS is highly recommended; Two T25 flasks Cultured Amniocytes or CVS (2x10^6 minimum); Parental/Patient: 3-5 ml whole blood or bone marrow, 3-4 buccal swabs and >=1 ugDNA at >=50 ng/uL
Minimum / Pediatric Volume Icon
Minimum / Pediatric Volume
Fetal: Call Laboratory; Parental/Patient: 2 ml
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Shipping Information
Room Temperature or Refrigerated
CPT Codes Icon
CPT Codes
  • 81401
Method Icon
Method
PCR and Hybridization Probes
Turnaround Time Icon
Turnaround Time
3-6 days
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New York State Approval
Approved
DEX Z-Code™ Icon
DEX Z-Code™
No
 
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Research investigators, postdoctoral fellows and laboratory staff at Versiti Blood Research Institute and Diagnostic Laboratories.
 
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