Publications
Tirthadipa “Dipa” Pradhan-Sundd and her research team have been published in a number of prestigious scientific and medical journals.
Selected Publications
View a full list of publications featuring Dr. Pradhan-Sundd.
- Kaminski TW, Katoch O, Li Z, Hanway CB, Dubey RK, Alagbe A, Brzoska T, Zhang H, Sundd P, Kato GJ, Novelli EM, Pradhan-Sundd T. Impaired hemoglobin clearance by sinusoidal endothelium promotes vaso-occlusion and liver injury in sickle cell disease. Haematologica. 2024 May 1;109(5):1535-1550. doi: 10.3324/haematol.2023.283792. PMID: 37941440; PMCID: PMC11063870.
- Katoch O, Ungalara R, Kaminski T, Li Z, Dubey RK, Burholt I, Gudapati S, Pradhan-Sundd T. Long-Term L-Glutamine Treatment Reduces Hemolysis without Ameliorating Hepatic Vaso-Occlusion and Liver Fibrosis in a Mouse Model of Sickle Cell Disease. Biomedicines. 2023 Aug 29;11(9):2412. doi: 10.3390/biomedicines11092412. PMID: 37760853; PMCID: PMC10526062.
- Pradhan-Sundd T, Kato GJ, Novelli EM. Molecular mechanisms of hepatic dysfunction in sickle cell disease: lessons from Townes mouse model. Am J Physiol Cell Physiol. 2022 Aug 1;323(2):C494-C504. doi: 10.1152/ajpcell.00175.2022. Epub 2022 Jun 27. PMID: 35759437; PMCID: PMC9359658.
- Vats R, Kaminski TW, Brzoska T, Leech JA, Tutuncuoglu E, Katoch O, Jonassaint J, Tejero J, Novelli EM, Pradhan-Sundd T, Gladwin MT, Sundd P. Liver-to-lung microembolic NETs promote gasdermin D-dependent inflammatory lung injury in sickle cell disease. Blood. 2022 Sep 1;140(9):1020-1037. doi: 10.1182/blood.2021014552. PMID: 35737916; PMCID: PMC9437711.
- Kaminski TW, Ju EM, Gudapati S, Vats R, Arshad S, Dubey RK, Katoch O, Tutuncuoglu E, Frank J, Brzoska T, Stolz DB, Watkins SC, Chan SY, Ragni MV, Novelli EM, Sundd P, Pradhan-Sundd T. Defenestrated endothelium delays liver-directed gene transfer in hemophilia A mice. Blood Adv. 2022 Jun 28;6(12):3729-3734. doi: 10.1182/bloodadvances.2021006388. PMID: 35427414; PMCID: PMC9631574.
- Vats R, Li Z, Ju EM, Dubey RK, Kaminski TW, Watkins S, Pradhan-Sundd T. Intravital imaging reveals inflammation as a dominant pathophysiology of age-related hepatovascular changes. Am J Physiol Cell Physiol. 2022 Mar 1;322(3):C508-C520. doi: 10.1152/ajpcell.00408.2021. Epub 2022 Jan 5. PMID: 34986022; PMCID: PMC8917937.
- Vats R, Kaminski TW, Pradhan-Sundd T. Intravital Imaging of Hepatic Blood Biliary Barrier in Live Mice. Curr Protoc. 2021 Oct;1(10):e256. doi: 10.1002/cpz1.256. PMID: 34610200; PMCID: PMC8500480.
- Vats R, Kaminski TW, Ju EM, Brozska T, Tutuncuoglu E, Tejero J, Novelli EM, Sundd P, Pradhan-Sundd T. P-selectin deficiency promotes liver senescence in sickle cell disease mice. Blood. 2021 May 13;137(19):2676-2680. doi: 10.1182/blood.2020009779. Erratum in: Blood. 2022 Aug 18;140(7):794. doi: 10.1182/blood.2021012644. PMID: 33619560; PMCID: PMC8120139.
- Pradhan-Sundd T, Gudapati S, Kaminski TW, Ragni MV. Exploring the Complex Role of Coagulation Factor VIII in Chronic Liver Disease. Cell Mol Gastroenterol Hepatol. 2021;12(3):1061-1072. doi: 10.1016/j.jcmgh.2021.02.014. Epub 2021 Mar 8. PMID: 33705963; PMCID: PMC8342958.
- Vats R, Ungalara R, Dubey RK, Sundd P, Pradhan-Sundd T. Heme-Oxygenase 1 Mediated Activation of Cyp3A11 Protects Against Non-Steroidal Pain Analgesics Induced Acute Liver Damage in Sickle Cell Disease Mice. Cells. 2025; 14(3):194.
- Kaminski TW, Zhang H, Katoch O, Shi Q, Kato GJ, Sundd P, Pradhan-Sundd T. Small molecule inhibitor screen to identify mechanisms controlling selective clearance of sickle hemoglobin by liver endothelial cells. Blood Vessels, Thrombosis & Hemostasis, 2025, 100045, ISSN 2950-3272.
Research
The Pradhan-Sundd lab’s research focuses on chronic organ injury and the processes of hepatic hemoglobin, heme and iron clearance in sickle cell disease.
Team
Get to know the members of the Pradhan-Sundd laboratory team at Versiti Blood Research Institute.
Image Gallery
Research images from the Pradhan-Sundd laboratory at Versiti Blood Research Institute.
Tirthadipa Pradhan-Sundd Laboratory
Tirthadipa “Dipa” Pradhan-Sundd’s laboratory at Versiti Blood Research Institute studies hepato-vascular cells in sickle cell disease and other hematological disorders.