Publications
Tirthadipa “Dipa” Pradhan-Sundd and her research team have been published in a number of prestigious scientific and medical journals.
Selected Publications
View a full list of publications featuring Dr. Pradhan-Sundd.
- Kaminski T, Katoch O, Li Z, Hanway CB, Dubey RK, Alagbe A, Brzoska T, Zhang H, Sundd P, Kato GJ, Novelli EM, Pradhan-Sundd T. Impaired hemoglobin clearance by sinusoidal endothelium promotes vaso-occlusion and liver injury in sickle cell disease. Hematologica. Manuscript accepted, in press. November 2023.
- Katoch O, Ungalara R, Kaminski T, Li A, Dubey RK, Burholt I, Gudapati S, Pradhan-Sundd T. Long-term l-glutamine treatment reduces hemolysis without ameliorating hepatic vasoocclusion and liver fibrosis in a mouse model of sickle cell disease. Biomedicines 2023, 11(9), 2412; Invited article for special issue on Sickle Cell Disease.
- Pradhan-Sundd T*, Kato GJ, Novelli EM. Molecular Mechanisms of Hepatic Dysfunction in Sickle Cell Disease: Lessons From The Townes Mouse Model. Am J Physiol Cell Physiol. 2022 Jun 27. doi: 10.1152/ajpcell.00175.2022. PMID: 35759437. Review. *first and corresponding author.
- Vats R, Kaminski TW, Brzoska T, Leech JA, Tutuncuoglu E, Katoch O, Jonassaint JC, Tejero J, Novelli EM, Pradhan-Sundd T, Gladwin MT, Sundd P. Liver to lung microembolic NETs promote Gasdermin-D-dependent inflammatory lung injury in Sickle Cell Disease. Blood. 2022 Jun 23:blood.2021014552. doi: 10.1182/blood.2021014552.PMID: 35737916.
- Kaminski TW, Ju E-M, Gudapati S, Vats R, Arshad S, Dubey RK, Katoch O, Tutuncuoglu E, Frank J, Brzoska T. Stolz DB, Watkins SC, Chan SY, Ragni MV, Novelli EM, Sundd P, Pradhan-Sundd T. Defenestrated endothelium delays liver directed gene transfer in Hemophilia A mice. Blood Advances, April 2022. PMID: 35427414.
- Vats R, Li Z, Ju EM, Dubey RK, Kaminski TW, Watkins S, Pradhan-Sundd T. Intravital imaging reveals inflammation as a dominant pathophysiology of age-related hepatovascular changes. Am J Physiol Cell Physiol. 2022 Jan 5. doi:10.1152/ajpcell.00408.2021. PMID: 34986022.
- Vats R, Kaminski T W, Pradhan-Sundd T. Intravital imaging of hepatic blood biliary barrier in live mice. August, 2021. Current protocols in Cytometry. 2021. PMID: 34986022.
- Vats R, Kaminski T, Ju E-M, Brozska T, Tutuncuoglu E, Tejero J, Novelli E, Sundd P, Pradhan-Sundd T. P-selectin deficiency promotes liver senescence in sickle cell disease mice. Blood. 2021 Feb 22:blood.2020009779. PMID: 33619560.
- Pradhan-Sundd T*, Gudapati S, Kaminski T, Ragni M. Exploring the complex role of procoagulant Factor VIII in chronic liver disease. Cellular molecular gastroenterology hepatology. Review Article. Cell Mol Gastroenterol Hepatol. 2021 Mar 8:S2352-345X(21)00052-7.PMID: 33705963.*first and corresponding author.
Research
The Pradhan-Sundd lab’s research focuses on chronic organ injury and the processes of hepatic hemoglobin, heme and iron clearance in sickle cell disease.
Team
Get to know the members of the Pradhan-Sundd laboratory team at Versiti Blood Research Institute.
Image Gallery
Research images from the Pradhan-Sundd laboratory at Versiti Blood Research Institute.
Tirthadipa Pradhan-Sundd Laboratory
Tirthadipa “Dipa” Pradhan-Sundd’s laboratory at Versiti Blood Research Institute studies hepato-vascular cells in sickle cell disease and other hematological disorders.