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Scanning electron micrograph of hepatic sinusoid showing liver sinusoidal endothelial fenestration (pores, green) in hemophilia mice.

Pradhan-Sundd Lab

The Pradhan-Sundd Laboratory explores hepato-vascular cells in sickle cell disease and other hematological disorders.

Tirthadipa Pradhan-Sundd Laboratory at Versiti Blood Research Institute

 

The Pradhan-Sundd Laboratory’s goal is to gain a better understanding of the involvement of hepato-vascular cells (liver sinusoidal endothelial cells, tissue resident macrophages and monocytes) in hematologic liver diseases. Our disease models include a humanized mouse model of sickle cell disease-induced acute and chronic liver injury, iron overload in the liver, murine models of hemolysis, vasculopathy, stressed erythrophagocytosis, and a mouse model of hemophilia.

 
Research
The Pradhan-Sundd lab’s research focuses on chronic organ injury and the processes of hepatic hemoglobin, heme and iron clearance in sickle cell disease.
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Publications
Tirthadipa “Dipa” Pradhan-Sundd and her research team have been published in a number of prestigious scientific and medical journals.
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Team
Get to know the members of the Pradhan-Sundd laboratory team at Versiti Blood Research Institute.
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Image Gallery
Research images from the Pradhan-Sundd laboratory at Versiti Blood Research Institute.
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Principal Investigator
Tirthadipa Tirthadipa profile

Tirthadipa Pradhan-Sundd, PhD

Associate Investigator

Transfusion Medicine, Vascular Biology & Cell Therapy

Assistant Professor
Department of Cell Biology, Neurobiology and Anatomy
Division of Hematology and Oncology
Medical College of Wisconsin

Education and Training

Postdoctoral Training
University of Pittsburgh School of Medicine

Doctoral Training
PhD, Simon Fraser University

Contact Information
  • AHamdan@Versiti.org
    • Tirthadipa Pradhan-Sundd Lab

    Lab Updates & News
    10/8/2023

    Congratulations Omika for your new post! We wish you all the very best from the Pradhan-Sundd lab.

    8/28/2023

    Congratulations to Ziming Li for his acceptance to NYU for post graduate studies!

    2/20/2023

    Congratulations Shweta! Our heart is swelled with joy as Shweta Gudapati got selected for both Temple and Stanford medical schools. She was the first undergrad of the Pradhan-Sundd Lab and worked with us for 3 years; published 3 papers and got many prestigous awards.

    12/28/2022

    Congratulations to Omika and Ziming for their poster presentations at the annual ASH meeting, 2022 held at NOLA.

    2/26/2022

    Congratulations to Ziming Li for his very first successful poster presentation at the Dept. of Biology Annual Undergraduate Symposium on his recent AJP-CP paper. Way to go Ziming!

    2/26/2022

    Pradhan-Sundd Lab is celebrating acceptance of full article at AJP-Cell Physiology!

    2/26/2022

    Shweta is selected for the final round of Goldwater Scholarship! Way to go Shweta!

    7/18/2021

    Shweta wins Capstone Grant from The Histochemical Society to study hepatic and extrahepatic sources of FVIII synthesis!

    2/4/2021

    Pradhan-Sundd lab is celebrating the acceptance of our article in Blood! Check it out.

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