Versiti - Christian Kastrup Lab | Versiti Blood Research Institute
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Understanding Blood Chemistry

To Design Tomorrow's Therapeutics
 

Innovative Hemorrhage Treatments

To Save Lives
 

Multidisciplinary RNA-Based Approaches

To Advance Hemostasis Research

Kastrup Lab

The Kastrup Lab is a multidisciplinary group of biochemists and engineers who investigate the biochemical and biophysical processes that regulate blood clotting. They use their discoveries to develop novel therapeutics for hemostasis and thrombosis based on RNA gene therapies, cellular therapies and nanomedicines.

Spidergram Illustration

Overview of Publications and Funding

Research Grants Publications & Patents
  • US Department of Defense - JWMRP
  • NIH R01 (Col-I)
  • Advancing a Healthier Wisconsin
  • American Heart Association
  • Nature Communications (Accepted and in Press)
  • Journal of Trauma and Acute Care Surgery
  • Journal of Military, Veteran and Family Health
  • Journal of Thrombosis and Haemostasis
  • Endoscopy International Open
  • Molecular Pharmaceutics
  • Injury
  • Blood
  • Military Medicine
  • Nature Cardiovascular Research
  • Spin-out company: SeraGene Therapeutics
  • PCT patent on antifibrinolytic RNA-LNP
  • Provisional patent on mRNA for rare bleeding
  • Provisional patent on PAI-1

Research Grants Publications & Patents
  • NIH R01 (Co-I)
  • Nanomedicines Innovation Network-SI
  • MITACS
  • US Department of Defense - RDTRA
  • CIHR Project Grant
  • Science
  • Extreme Mechanics Letters
  • Transfusion
  • Journal of Thrombosis and Haemostasis
  • Endoscopy Open International
  • Provisional patent on RNA-edited platelets
  • Provisional patent on ADAMTS13

Research Grants Publications & Patents
  • US Department of Defense - MuLTI
  • US Department of Defense - PRMRP
  • Nanomedicines Innovation Network
  • CFI John R. Evans Leaders Fund
  • Blood
  • Endoscopy Open International
  • Journal of Thrombosis and Haemostasis
  • Blood Advances
  • Scientific Reports
  • Res Pract Thromb Haemost
  • Blood Advances
  • ACS Nano
  • Biochemistry
  • Provisional patent on RNA-edited platelets
  • Provisional patent on ADAMTS13

Research Grants Publications & Patents
  • Bayer Hemophilia Award
  • J. Thromb. & Haem.
  • Scientific Reports
  • Patent issued on hemostatic particles

Research Grants Publications & Patents
  • NSERC Discovery Grant
  • Blood Coag. & Fibrin.
  • J. Biol. Chemistry
  • J. Thromb. & Haem.
  • J. Thromb. & Haem.
  • Provisional patent on antithrombotic siRNA

Research Grants Publications & Patents
  • Novo Access to Insight
  • Scientific Reports
  • Ann. Rev. of Biochem
  • Laryngoscope
  • Provisional patent on liposomal thrombin
  • Spin-out company: CoMotion

Research Grants Publications & Patents
  • CFI John R. Evans Leaders Fund
  • J. Thromb. & Haem.
  • Shock
  • Thrombosis Research
  • Biomacromolecules
 
7

Graduate Students

 
3

Post Docs

 
38

Fellowships and Awards

 
60

Undergrads Mentored

 
16

Patents Filed

 
60

Publications

 
8.5

Average Impact Factor

What's New

January - Research Trainee, Amanda Wietrzny, was accepted into the interdisciplinary Program at the Medical College of Wisconsin for Fall 2023. She will be pursuing her PhD in Biochemistry. Good luck, Amanda!

February - Visiting PhD student Matteo Ferraresso joins the lab from the University of British Columbia. Welcome Matteo!

March - Manoj Paul is joining the lab from the University of British Columbia! Welcome Manoj!

September - Dr. Mitch Dyer joins the lab as an Adjunct Associate Investigator. Dr. Dyer is also an Assistant Professor in Vascular Surgery at MCW. Welcome, Dr. Dyer!

October - Youjie Zhang has started as a Graduate Student in the Kastrup lab! Youjie is studying Biomedical Engineering through a joint program between Marquette and MCW. Good luck, Youjie!

November - Our surgical Resident, Monica Seadler, gave birth to a little girl, Lillian. Congratulations, Monica!

Related Content
 
Research
We are a group of biochemists and engineers working to gain a deeper understanding of how blood clotting is regulated and can be controlled therapeutically.
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Publications
A list of biomedical-related publications published or co-published by the Christian Kastrop Laboratory.
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Personnel
Our lab is a positive and collaborative environment that prepares trainees for highly successful careers in science and engineering fields of academia, industry, and government.
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Contact Us
Learn more about our where the Christian Kastrup Laboratory is located and a contact us form to apply or make an inquiry.
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