Matthew Anderson, MD, PhD

Matthew  Matthew  profile

Matthew Anderson, MD, PhD

VP and Medical Director, Diagnostic Laboratories, Associate Investigator

Immunobiology

Education and Training

B.S., University of California San Diego (1995) 
M.D., Ph.D., Medical College of Wisconsin, Medical Scientist Training Program (2006)
Resident, Anatomic Pathology, Stanford University Medical Center (2006-08) 
Fellow, Hematopathology, Stanford University Medical Center (2009-10 
Fellow, Molecular Genetic Pathology, Stanford University Medical Center (2010-11) 
Director-in-Training, Stanford Histocompatibility, Immunogenetics, and Disease Profiling 
Laboratory, Department of Pathology, Stanford University School of Medicine (2010-11) 

Board Certifications

Anatomic Pathology, American Board of Pathology (2010) 
Molecular Genetic Pathology, American Board of Pathology and American Board of Medical 
Genetics (2012) 

Contact Information
  • 414-937-6419
  • 414-937-6419
  • My research interests include the use of high-throughput sequencing technologies for clinical diagnostics and biomarker discovery, focused on transplantation and the molecular pathogenesis of lymphoma. Human leukocyte antigens (HLA) are key molecular determinants of the adaptive immune response, and also control the host immune response to bone marrow and solid-organ transplants. Clinically, the success of a transplant critically depends on a high degree of similarity between the HLA molecules of the donor and recipient. However, HLA genes are among the most polymorphic in the human genome, complicating our efforts to genotype patients using standard DNA sequencing techniques. Our recent work has demonstrated that newer high-throughput sequencing technologies can improve the accuracy of HLA genotyping by virtue of clonal template amplification and sequencing, and we are currently adapting this approach for routine clinical histocompatibility testing. In the future, we plan to broaden the use of high-throughput sequencing technologies to analyze other genes important for the immune response to transplants and to monitor patients for rejection.

     
    Diagnostic Laboratories
    Diagnostic laboratory services including HLA testing, donor testing, immunohematology reference lab testing, hematology testing and more.
     
    Our Experts
    Research investigators, postdoctoral fellows and laboratory staff at Versiti Blood Research Institute and Diagnostic Laboratories.
     
    Immunobiology
    We study the development and function of the immune system and design immunomodulating therapies for infection, autoimmune disease, and cancer.
     
    Versiti Blood Research Institute
    Versiti Blood Research Institute investigators study blood disorders like hemophilia, blood cancers like leukemia, and other blood diseases.