Versiti - Matthew Kudek, MD | Versiti Blood Research Institute

Matthew Kudek, MD

Matthew Matthew profile

Matthew Kudek, MD

Associate Investigator (adjunct)


Assistant Professor of Pediatric Hematology
Department of Hematology, Oncology, and Bone Marrow Transplant (BMT)
Medical College of Wisconsin

Associate Investigator (adjunct)
Blood Research Institute Versiti

Contact Information

Our research focus is on T cell biology, specifically pertaining to mechanisms underlying T cell exhaustion and dysfunction. This includes a focus on tumor infiltrating lymphocytes and understanding the mechanisms leading to tumoral immune escape. We are also interested in the development of novel therapeutic approaches to reprogram dysfunctional tumor infiltrating lymphocytes towards an effector phenotype to promote tumor clearance.

  • St. Baldrick's Foundation Fellowship, "Pathogen Boosted Adoptive Cell Transfer for the Treatment of Neuroblastoma," Role: PI (2021-23)
  • Children's Research Institute, "Dissecting the Cellular Mechanisms of Differential Outcomes of CD20-19 CAR-T Therapy in Acute Lymphoblastic Leukemia (ALL)," Role: Co-Investigator (2020-22)
  • Vince Lombardi Cancer Research Foundation, "CD19-20 CAR T Trial," Role: Co-Investigator (2020-21)

View the complete list of publications here:

  1. Kudek MR, Shanley R, Zantek ND, McKenna DH, Smith AR, Miller WP. Impact of Graft-Recipient ABO Compatibility on Outcomes after Umbilical Cord Blood Transplant for Nonmalignant Disease. Biol Blood Marrow Transplant. 2016 Nov;22(11):2019-2024. PMCID: PMC5067229
  2. Topchyan P, Xin G, Chen Y, Zheng S, Burns R, Shen J, Kasmani MY, Kudek M, Yang N, Cui W. Harnessing the IL-21-BATF Pathway in the CD8+T Cell Anti-Tumor Response. Cancers (Basel). 2021 Mar 12;13(6):1263. PMCID: PMC7998696.
  3. Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W. E2A-regulated epigenetic landscape promotes memory CD8 T Cell differentiation. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2013452118. PMCID: PMC8072256.

Click here to view a story done by Fox6 Milwaukee about Dr. Kudek's grant from St. Baldrick's Foundation $200K fellowship for Children's Wisconsin doctor fighting neuroblastoma

Join Versiti Blood Research Institute
Versiti Blood Research Institute, located in Milwaukee, Wisconsin, includes basic and clinical researchers in a variety of blood health fields.
Our Investigators
Browse our Investigators, Emeritus Investigators, and other members of the Blood Research Institute.
VBRI Education
Versiti Blood Research Institute researchers and staff have access to medical research seminars, fellowships, training opportunities and more.
Versiti Blood Research Institute
Versiti Blood Research Institute investigators study blood disorders like hemophilia, blood cancers like leukemia, and other blood diseases.